A new possibility has emerged to combat the errors resulting in a number of genetically determined diseases including cancers and some forms of Alzheimer’s, as well as contributing to ageing as a major breakthrough has been achieved in the field of genes.

Science has taken a new leap in the field of genes as their ability to recognize similarities in each other from a distance, without any proteins or other biological molecules aiding the process, has been discovered according to new research published this week in the “Journal of Physical Chemistry “.

This new study sheds light on the ability of the genes - which are parts of double-stranded DNA with a double-helix structure containing a pattern of chemical bases – to recognize other genes with a similar pattern of chemical bases.

This study has been able to provide the scientists a useful clue to understand the mechanism of the genetic identification and alignment with each other in order to facilitate the process of ‘homologous recombination’ - whereby two double-helix DNA molecules come together, break open, swap a section of genetic information, and then close themselves up again.

Recombination is an important process which plays a key role in evolution and natural selection, and also controls the body’s ability to repair damaged DNA. The information was really confined in regards to the genes ability to recombine them till now.

A series of experiments have been conducted to reach the conclusion that long pieces of identical double-stranded DNA could identify each other merely as a result of complementary patterns of electrical charges which they both carry. This happens without any physical contact between the two molecules, or the facilitating presence of proteins. It also found that the length of the genes also determines the strength of the recognition mechanism between the two genes.

The behavior of fluorescently tagged DNA molecules in a pure solution was observed which led to the discovery that chances of DNA molecules with identical patterns of chemical bases to recognize and recombine than DNA molecules with different sequences.
A new set of experiments are designed to explore further how these interactions work, the impact of gene length on this mechanism and possibility to carry out this interaction in a highly complex mechanism of a living cell , which is till now limited to the closed environment of a test tube team.

Understanding this mechanism of the primary recognition stage of genetic recombination promises a strong aid to control the genetically determined diseases and also an important breakthrough in the field of biotechnologies and gene therapies.

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